Histopathological effectiveness of vitex agnus castus in treating polycystic ovaries induced by letrozole in female rabbits

Authors

  • Mohammed Jasim Jawad Physiology, Pharmacology and Biochemistry Department, Veterinary Medicine College, University of Kerbala, Karbala, Iraq.

DOI:

https://doi.org/10.59658/jkas.v10i2.1183

Keywords:

Vitex agnus-castus, polycystic Ovaries, clomiphene citrate

Abstract

Female fertility is significantly impact by the common endocrine health issue known as polycystic ovarian syndrome (PCOS) in the childbearing years, Due to their ease of use and reduced cost-effectiveness when compared to chemical medicines generated via synthesis, therapeutic wild plants and herbs have been prized agents in the management of different illnesses for ages. Premenstrual syndrome, mastalgia, infertility, and menstrual cycle control are among the numerous conditions and diseases that can be treated with Vitex agnus-castus, a well-known medicinal plant that is native to the Mediterranean region and is widely used in Europe, Asia, and North Africa. The purpose of the study is to learn more about Vitex agnus catus and evaluate its efficacy in treating polycystic ovaries induced by letrozole in comparison to clomiphene citrate therapy. Since the effects of herbal activity are assessed by, observing histopathological changes in rabbit ovaries. The incidence of subcapsular ovarian cysts, capsular thickness, incomplete luteinization, and the quantity of corpora lutea were all higher in the research groups' ovaries. Compared to the group with a positive control (treated with normal saline only and administered orally). Histopathological study of the rabbit ovaries for both treatment groups revealed hyperplasia of the surface epithelium and congested blood vessels of the ovaries.

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Published

06/18/2023

How to Cite

Jasim Jawad, M. . (2023). Histopathological effectiveness of vitex agnus castus in treating polycystic ovaries induced by letrozole in female rabbits. Journal of Kerbala for Agricultural Sciences, 10(2), 33–42. https://doi.org/10.59658/jkas.v10i2.1183

Issue

Vol. 10 No. 2 (2023): Volume 10 Issue 2 2023

Section

Articles

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