A Study of the Relationship Between Age, Gender, and Some Immunological Parameters in Patients with Celiac Disease in Karbala Province

Abstract

Celiac Disease (CD) is a public hereditary, autoimmune and multifactorial gastro-intestinal disorder in children and adults defined as a permanent gluten-sensitive enteropathy. The current study aimed to investigate the effect of age and gender factors on the incidence of celiac disease and to evaluate some immunological parameters in the diagnosis of wheat allergy, through a sample of 303 persons suspected of being infected with celiac disease who attended Imam Al-Hassan Al-Mujtaba Hospital in Karbala Governorate for the period from 1/ 2/2022 to 1/9/2022. The questionnaire was prepared and filled with information about celiac disease. The results of the current study showed that the number of infections with celiac disease is 65 out of 188 in females, while in males was 42 out of 115. The number of infected males was 23 out of 42, while the number of females was 30 out of 65 within children category of celiac disease. The results also showed that there were significant differences in the level of TTG IgA, and TTG IgG between males and females.