Atherogenic Indices for Cardiovascular Outcomes in Patients with Chronic Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A Key Role or Standby

Abstract

Background: This study explores the link between atherogenic indices and cardiovascular outcomes in patients with chronic coronary syndrome (CCS) undergoing percutaneous coronary intervention (PCI). It aims to determine if these indices can provide valuable prognostic information for risk stratification and personalized treatment strategies.

Method: A retrospective study analyzed medical records of 120 CCS patients, revealing 72 underwent PCI and 48 underwent Catheter Angiography.AC, AIP, Castelli’s I , II and C-index were determined as non-HDL / HDL , log (TG/ HDL) , TC/ HDL , LDL / HDL  and  LDL– HDL respectively.

Results: The study compared atherogenic indices between PCI patients and CA patients, finding that CA patients had significantly higher values for most atherogenic indices despite a seemingly better lipid profile. The CA group has a significantly higher C-index (85.8 ± 18.7) compared to the PCI group (37.1 ± 57.4), indicating a potentially greater risk of atherosclerotic events in the CA group. The PCI group has a slightly higher average AIP (0.7 ± 0.5) compared to the CA group (0.6 ± 0.1). The CA group has higher values for both Castelli's indices (I: 5.4 ± 0.7, II: 3.6 ± 0.6) compared to the PCI group (I: 4.0 ± 1.9, II: 2.0 ± 1.8). The CA group has a higher average AC index (4.4 ± 0.7) compared to the PCI group (3.0 ± 1.9).

Conclusion: Daily practice should consider parameters like AC, AIP, CR I&II, which can better reflect complex lipid metabolism and are more easily calculated than traditional lipid parameters.