Serum Adiponectin Marker in Women with Polycystic Ovary Syndrome

Yasameen Imad  Kadhim; Fadhil Jawad  Al-Tu’ma; Nora Sabah  Rasoul

doi:10.62472/kjps.v14.i23.22-30

المؤلفون

Yasameen Imad Kadhim Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala/ Kerbala –Iraq
Fadhil Jawad Al-Tu’ma Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala/ Kerbala –Iraq
Nora Sabah Rasoul Department of Obstetrics and Gynecology, College of Medicine, University of Kerbala, Iraq

DOI:

https://doi.org/10.62472/kjps.v14.i23.22-30

الكلمات المفتاحية:

Adiponectin، polycystic ovarian syndrome، insulin resistance

الملخص

Background: One of the leading causes of female infertility is polycystic ovarian syndrome (PCOS). Adiponectin is one of many adipokines adipose tissue releases that affect insulin resistance (IR).

Objective: To measure PCOS participants' IR, adiponectin, and serum insulin levels.

Materials and Procedures: a case-control study involving 80 patients with PCOS (40 obese and 40 nonobese) and 80 controls (40 obesity and 40 nonobese). Adiponectin was measured using an enzyme-linked immunosorbent assay, while serum levels of insulin and FBS were measured using a chemiluminescent automated immunoassay system (ECL).

Results: Regardless of body mass index and PCOS, women had lower levels of adiponectin and higher levels of blood fasting glucose, insulin, and IR compared to the relevant with a p-value of ≤0.001 for controls. Conclusion: According to weight, blood adiponectin levels inversely correspond to IR. It can, therefore, act as an indicator in PCOS-affected women.