Study of The Effect of Combination of Some Medicinal Plant Extract Against Candida albicans Isolated From Clinical Sourse

الملخص

Background: Candida albicans are opportunistic pathogens that affect mucosal, dermal, urogenital, and gastrointestinal areas, necessitating the search for effective treatments against them. Recently, plant extracts such as Garlic (Allium sativum), Ginger (Z. officinale), myrrh (Commiphora myrrha), and propolis have been used to treat infections caused by these yeasts. Methods: The Candida albicans were isolated and identified from their different clinical sources, alcoholic extracts were prepared at different concentrations (10, 25, 50, 75, 100) mg ml-1to study of inhibitory effect of alcoholic extracts of Garlic, Ginger, Myrrh and Propolis each alone and mixed with Ginger against C. albicans. Results: The results showed all alcoholic extracts had variable inhibitory effect against yeast growth, with the concentration of 100 mg ml-1 recording the highest inhibitory effect, while the alcoholic extract of propolis at a concentration of 50 mg ml-1 was the most effective. It was also shown, by study of the combination (mixing) between alcoholic Ginger extract and other extracts, that there different degrees of inhibition of yeast growth Conclusions: The study revealed the importance of plant extracts' effect when mixed to control resistant C. albicans that threaten human health.