Phytochemicals Screening and Antimicrobial Activity of Veronica Agrastis Extract

Abstract

           Phytochemical compounds are of medical importance for many diseases, including inhibitory activity against bacterial and fungal pathogens. In this paper , multiple phytochemicals were isolated from Veronica agrestis in Iraq by subjecting the stem and leaves to gas chromatography-mass spectrometry (GC-MS). The study aims to identify the active compounds of the vegetative parts of the species and test their inhibitory activity against pathogens. The analysis revealed the presence of ten biologically active phytochemicals: benzeneacetonitrile, 3-hydroxy; (E)-4-(3-hydroxyprop-1-en-1-yl)-2;methoxyphenol; phytol; 9,12,15,-octadecatetrienoic acid (Z,Z,Z); 13,17Seco-5 pregn-13(18)-n-20-one; stigmasterol; octatriacontyl pentafluoropropionate; 5-(7a-isopropyl-4,5-dimethyl-octahydroindin-4-yl)-3-methyl-penta-2,4-dien-1-ol; cholestan-3-ol; 2-Methylenediamine-,(3β,5α)-. These compounds showed high inhibitory activity against the pathogenic fungus Candida albicans and the bacteria Proteus mirabilis. Six concentrations of the extract were used ( 5 ,10, 20 ,40 ,60 ,80 )mg/ml  showed  results (00.00, 0.00, 0.00, 6.00,10.00,16.00) mm diameter of colonies in Candida albicans  whil the diameter of colonies in Proteus mirabilis  presented results (0.00,0.00, 10.00, 14.00, 22.00, 30.00) mm  respectivly .